& Elmlinger, M
SS-31 has anti-apoptotic properties, meaning it can inhibit programmed cell death
With this background, GLP-1RAs might provide an opportunity to break the remarkable inflammation process, exerting broad anti-inflammatory actions and reducing biomarkers of systemic inflammation in particular in human subjects with type 2 diabetes and people with obesity ( Despite a large body of scientific research, GLP-1RA demonstrated a positive effect with a 14% reduction in major cardiovascular events (MACE) [HR=0.86, 95%CI(0.79-0.94), p =0.006] and no significant heterogeneity was observed between subgroups of individuals with or without cardiovascular disease ( p =0.127)
It was shown that oven-drying of germinated wheat grains at 50 C did not affect the folate content, so it did not decrease the improved nutritional value of germinated grains 421,503
Standard diabetes and weight management monitoring should continue as per NICE guidance, including HbA1c measurement, cardiovascular risk assessment, and monitoring for common GLP-1 adverse effects such as gastrointestinal symptoms
Lim J, Kim E, Noh HJ, Kang S, Phillips BU, Kim DG, et al